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Welcome to The Visible Embryo, a comprehensive educational resource on human development from conception to birth.

The Visible Embryo provides visual references for changes in fetal development throughout pregnancy and can be navigated via fetal development or maternal changes.

The National Institutes of Child Health and Human Development awarded Phase I and Phase II Small Business Innovative Research Grants to develop The Visible Embryo. Initally designed to evaluate the internet as a teaching tool for first year medical students, The Visible Embryo is linked to over 600 educational institutions and is viewed by more than ' million visitors each month.


WHO International Clinical Trials Registry Platform
The World Health Organization (WHO) has created a new Web site to help researchers, doctors and patients obtain reliable information on high-quality clinical trials. Now you can go to one website and search all registers to identify clinical trial research underway around the world!



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Pregnancy Timeline by SemestersFemale Reproductive SystemFertilizationThe Appearance of SomitesFirst TrimesterSecond TrimesterThird TrimesterFetal liver is producing blood cellsHead may position into pelvisBrain convolutions beginFull TermWhite fat begins to be madeWhite fat begins to be madeHead may position into pelvisImmune system beginningImmune system beginningPeriod of rapid brain growthBrain convolutions beginLungs begin to produce surfactantSensory brain waves begin to activateSensory brain waves begin to activateInner Ear Bones HardenBone marrow starts making blood cellsBone marrow starts making blood cellsBrown fat surrounds lymphatic systemFetal sexual organs visibleFinger and toe prints appearFinger and toe prints appearHeartbeat can be detectedHeartbeat can be detectedBasic Brain Structure in PlaceThe Appearance of SomitesFirst Detectable Brain WavesA Four Chambered HeartBeginning Cerebral HemispheresEnd of Embryonic PeriodEnd of Embryonic PeriodFirst Thin Layer of Skin AppearsThird TrimesterDevelopmental Timeline
Click weeks 0 - 40 and follow fetal growth
Google Search artcles published since 2007
 
October 7, 2011--------News Archive

High Level of Fried Food Toxins Found in Infants
Advanced Glycation End products (AGEs) are found in most heated foods and in commercial infant formulas. Also found, reducing AGEs improves adult diabetes.

‘Genetic Biopsy’ Could Help Pick Best Eggs for IVF
Analyzing genetic material in polar bodies, shed at fertilization, can yield information about gene expression in the egg without disturbing the egg itself.

Sox2 Marks Pluripotency in Most Adult Stem Cells
Sox2 appears to be the only transcription factor appearing in all stem cell stages – embryonic, fetal and adult. It may also indicate pluripotent adult stem cells.

Stem Cell Reprogramming Safer than Thought
Selecting better donor cells and using more sensitive genome-survey techniques allows identifying and reprogramming methods safer than in current use.

October 6, 2011--------News Archive

Invasive Melanoma Higher in Children Than Adults
A study of young people with melanoma, a deadly form of skin cancer, has found that some children have a higher risk of invasive disease than adults.

All Human Egg Donors Should Be Compensated
When you donate your eggs to fertility clinics for infertile parents, you are compensated. But if you donate your eggs for stem research, you are not.

Chronic Stress Short-circuits Some Parents
Moms with higher depressive responses exhibit symptoms of extreme stress with distinct types of problem parenting, from neglect and hostility to insensitivity.

October 5, 2011--------News Archive

Intensive Exposure Best for Reading Difficulties
Intensive daily training for a limited period is better for children with reading and writing difficulties than the traditional remedial tuition offered by schools.

A Shot of Cortisone Will Stop Traumatic Stress!
A single injection of cortisone can prevent PTSD in 60% who experience trauma.

Asthma Guidelines Do Not Reduce Readmissions
Hospital compliance with The Children's Asthma Care (CAC) guidelines makes little difference in a patient's return for another asthma attack.

October 4, 2011--------News Archive

How the Brain Makes Memories: Rhythmically!
The brain learns through changes in the strength of its synapses in response to stimuli. However, the stimulus must be rhythmic - timed at exact intervals.

Anesthesia Exposure Linked to Learning Disability
Research has found a link among children undergoing multiple surgeries requiring general anesthesia before age 2 and learning disabilities later in childhood.

How Vertebrates Establish Left–Right Asymmetry
Although we appear bilaterally symmetrical on the outside, our internal organs are asymmetrically positioned along a left–right axis.

October 3, 2011--------News Archive

Glucosamine-like Supplement Suppresses MS Attacks
UCI study shows promise of metabolic therapy for autoimmune diseases.

Early to Bed and Barly to Rise - Keeps Kids Lean
Bedtime found to be as important for preteens and teens as getting enough sleep.

Discovered: "Flexible" Brain DNA Changes to Suit
Finding has implications for treatment of wide range of diseases.

Mother's Love Unravels Gene Sequencing Mystery
A mother's determination solves the strange symptoms in her twins. Personalized medicine through genome sequencing is working for this family.

Genome Architecture Foretells Genome Instability
In normal cell division, DNA gets copied perfectly and distributed between daughter cells evenly. But occasional breaks during division rearrange the results.

WHO Child Growth Charts

In the best of circumstances, raising a toddler is daunting. But parents under long-term stress often find it near impossible to tap into the patience, responsiveness, and energy required for effective child rearing.

Now research from a University of Rochester team helps to explain why chronic stress and parenting are such a toxic mix. The study finds that ongoing strains, like poverty or depression, disrupt the body's natural stress response, making mothers more likely to engage in a host of problematic parenting behaviors, including neglect, hostility, and insensitivity.

"Stress gets under your skin," explains Melissa Sturge-Apple, assistant professor of psychology at the University of Rochester and lead author on the Development and Psychopathology paper to be published October 19.

"It literally changes the way a mother's body responds to the normal demands of small children and those changes make it much harder to parent positively."

Although the effects of stress have been well documented in children and linked to a variety of diseases in adults, this is one of the first studies to look specifically at stress and parenting.

The findings point to the corrosive effects of poverty or depression on an individual's physiology and help to explain why people feel and act the way they do when faced with ongoing psychological or economic pressure, she says.

"Stress is not just in our heads, it's in our bodies," says Sturge-Apple.

This is also the first study to measure physiological stress response in real time, says Fred Rogosch, research director at the University of Rochester's Mt. Hope Family Center and a fellow author on the paper. Participants' reactions were captured using a new wireless electrocardiograph (ECG) monitor developed for the study by University of Rochester engineers Zeljko Ignjatovic and Wendi Heinzelman.

The unobtrusive device allowed the team to analyze subtle changes in participants' heart rhythms as they were happening, providing a non-behavioral window into how the study moms were reacting. Other methods, such as measuring the stress hormone cortisol, require a 20-minute delay and are not nearly as precise, explains Rogosch.

The new monitor could become an important tool for measuring stress outside of the lab, the authors write. For example, it could be used in clinical settings as a kind of emotional biofeedback monitor, giving therapists a way to quantitatively gage which therapies work best for alleviating negative emotions, according to the researchers.

In the study, the researchers observed 153 mothers and their 17-to-19-month-old children in individual two-hour sessions. Using the wireless ECG monitor, each mother's stress response was measured during a mildly distressing situation in which her child was left with a stranger for a few minutes. Later the mother and toddler were videotaped during unstructured playtime together.

The study showed that a mother's stress system can be compromised by becoming either overactive or underactive.

Mothers with higher depressive symptoms exhibited overactive stress responses, the “hyperarousal” pattern shown in red, while moms who struggled with poverty had underactive responses, the “hypoarousal” patter shown in blue. Each extreme was associated with distinct types of problematic parenting, from neglect and hostility to insensitivity.

In mothers with higher depressive symptoms, stress responses were "hyperactive", researchers found. These moms' heart rate patterns began higher, then spiked when their toddler beame upset. After the mom was reunited with the child, their heart rate pattern remained elevated. During the free-play sessions, mothers with hyperactive stress responses engaged in the highest levels of hostility with their toddler, including derogatory comments, angry tone of voice, and rough physical interaction.

Although the popular image of depression is of someone who is listless and sad, Sturge-Apple points out that the study confirms what clinicians have long observed: that depression in mothers sometimes is linked to harsh, highly reactive parenting, not subdued mothering.

This study helps to explain the biological basis of such behavior; the stress response systems of moms suffering from depression are on high alert, oversensitive to social stressors and unable to calm down, explains Sturge-Apple.

In contrast, study participants who struggle with poverty and live in high-crime neighborhoods exhibited underactive, or "hypoactive," stress response systems. Their heart rates patterns began lower and rose little during their child's distress.

During free play, these parents showed the highest levels of disengagement along with intrusive parenting. Although instructed to play with their children, these mothers were more likely to ignore their little ones and not respond to children's bids for attention or play. When they were engaged, mothers with hyporesponsive stress activity were overbearing.

The researchers argue that the dampened physiological response to a child's anguish results from the "cumulative wear and tear … of living in poverty and dangerous neighborhoods."

Faced with threats and concerns on a daily basis, these moms' stress systems simply become overwhelmed, concludes Sturge-Apple.

The research was supported by the National Institute of Nursing Research. Michael Skibo, a doctoral student in social and clinical psychology at the University of Rochester, also contributed to the publication.

The University of Rochester (www.rochester.edu) is one of the nation's leading private universities. Located in Rochester, N.Y., the University gives students exceptional opportunities for interdisciplinary study and close collaboration with faculty through its unique cluster-based curriculum. Its College, School of Arts and Sciences, and Hajim School of Engineering and Applied Sciences are complemented by its Eastman School of Music, Simon School of Business, Warner School of Education, Laboratory for Laser Energetics, School of Medicine and Dentistry, School of Nursing, Eastman Institute for Oral Health, and the Memorial Art Gallery.

Original article: http://www.rochester.edu/news/show.php?id=3913